My Friends Care: The Bone Marrow Donation Process

The Bone Marrow Donation Process

A small amount of blood (about two to three tablespoons) is taken from the volunteer donor at an NMDP (National Marrow Donor Program)-approved donor center or recruitment drive site.
The sample is typed for markers on the surface of white blood cells (called HLA-AB and DR antigens) and the results are entered on the computerized NMDP Registry.
If all six antigens match, the donor is counseled about the donation process and given a physical examination after a thorough information session. The donor makes the final decision to donate and signs the consent form.
Donated marrow is extracted in a simple surgical procedure under general or spinal anesthesia at an NMDP-approved Collection Center (Hospital). Two to five percent of the donor's marrow is extracted from the back of the pelvis through a special needle and syringe.
The donor is usually kept in the hospital overnight for observation.
After the marrow collection procedure, the donor may experience slight discomfort for a week or so in the lower back. The donor's marrow replenishes itself within a few weeks.